What does progression mean in cancer?

What does progression mean in cancer?

Listen to pronunciation. (pruh-GREH-shun) In medicine, the course of a disease, such as cancer, as it becomes worse or spreads in the body.

What is progression-free survival in cancer?

The length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse. In a clinical trial, measuring the progression-free survival is one way to see how well a new treatment works. Also called PFS.

What does clinical progression mean?

Physicians use many terms to describe the progress of a cancer or its response to treatment, one of which is progressive disease. Progressive disease means what the term implies, that a cancer is getting worse, but these terms are used to explain exactly how much worse a cancer appears to be.

What does it mean when cancer is in regression?

In cancer, regression refers to a specific decrease in the size or extent of a tumour. In histopathology, histological regression is one or more areas within a tumor in which neoplastic cells have disappeared or decreased in number.

What is an example of progression?

A progression is a series that advances in a logical and predictable pattern. In mathematics, for example, the series 2, 4, 6, 8 is an arithmetic progression. If asked to give the next number, most people would reply 10.

What does time to progression mean?

pruh-GREH-shun) The length of time from the date of diagnosis or the start of treatment for a disease until the disease starts to get worse or spread to other parts of the body. In a clinical trial, measuring the time to progression is one way to see how well a new treatment works. Also called TTP.

Is progression-free survival the same as time to progression?

Progression-free survival (PFS) is defined as the time from randomization to tumor progression or death. The US Food and Drug Administration (FDA) favors PFS as a surrogate endpoint because it accounts for patients who die following tumor progression or following adverse events related to treatment.

Does progression-free survival include death?

Progression-free survival (PFS) is defined as the time from random assignment in a clinical trial to disease progression or death from any cause.

What is considered causes of disease progression?

Disease progression describes the natural history of disease, such as pain, or biomarker of drug response, such as blood pressure. The action of a drug, such as inhibiting an enzyme or activating a receptor, leads to a change in disease status over time.

Is there spontaneous regression of malignant tumor?

On the basis of data from the literature, it can be concluded that almost all types of malignant tumors can regress spontaneously, although some histological types regress more frequently than others. Moreover, when referring to cases of metastases, the regression can escape observation more often than anticipated.